News

  Bone is a remarkable material, strong enough to withstand impressive forces without fracturing. Despite decades of research, however, our understanding of the molecular mechanisms underlying bone’s fracture resistance has remained incomplete. It has long been hypothesized that collagen degradation occurs following bone fracture. Until recently, this hypothesis lacked empirical evidence due to a...

  Chronic kidney disease (CKD) progressively impairs kidney function, affecting millions. Beyond kidney-related complications, patients often experience muscle weakness and reduced mobility, begging the question: does muscle fibrosis contribute to those limitations? Figure 1 demonstrates a significant increase in collagen deposition within the vastus lateralis muscle of CKD patients. Histochemical analysis using picro-sirius red...

Atherosclerosis, characterized by the buildup of plaque inside human arteries, is one of the leading causes of cardiovascular diseases. The disease is brought on by a complex interplay between lipids, inflammatory cells, and the ECM. Arterial blood flow is restricted as plaques form, which can rupture to cause blockage. Arterial blockage, or occlusion, is...

Biliary Atresia (BA) is a severe liver disease in infants, often leading to cirrhosis and death. Collagen Hybridizing Peptides (CHP) offer diagnostic and prognostic insights, aiding treatment decisions and organ transplant allocation.

Explore more about the impact of obesity-related pre-diabetic hyperglycemia on bone healing using the DIO mouse model. CHPs help reveal that deficits in collagen microstructure leads to impaired fracture healing in obese subjects.

3Helix is thrilled to announce the addition of three new members to our talented team.  These new members bring with them experience and expertise that will contribute to our continued success. It is our pleasure to introduce Regan, Keelah, and Anthony to you all. Please help us congratulate them on joining our team! We...