First Empirical Evidence of Collagen Damage during Bone Fracture
Bone is a remarkable material, strong enough to withstand impressive forces without fracturing. Despite decades of research, however, our understanding of the molecular mechanisms underlying bone’s fracture resistance has remained incomplete. It has long been hypothesized that collagen degradation occurs following bone fracture. Until recently, this hypothesis lacked empirical evidence due to a...
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Delayed Fracture Healing in Obesity-associated Type 2 Diabetic Mouse Model
Explore more about the impact of obesity-related pre-diabetic hyperglycemia on bone healing using the DIO mouse model. CHPs help reveal that deficits in collagen microstructure leads to impaired fracture healing in obese subjects.
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